Sermorelin
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Sermorelin is an analog of growth hormone-releasing hormone (GHRH) that stimulates the pituitary gland to secrete endogenous growth hormone (GH). By promoting the release of natural GH, Sermorelin enhances muscle growth, fat metabolism, tissue repair, and overall anabolic processes. It also increases the production of insulin-like growth factor-1 (IGF-1), which is essential for muscle repair, regeneration, and overall growth. Sermorelin works by mimicking the body's natural pulsatile release of GHRH, supporting long-term physiological balance.
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Stimulates the release of growth hormone (GH) from the pituitary gland.
Enhances muscle growth and strength.
Reduces fat mass and improves body composition.
Increases bone density and supports skeletal health.
Improves physical performance and recovery from exercise.
Enhances sleep quality and promotes deep, restorative sleep.
Supports skin health by increasing collagen production.
Improves energy levels and reduces fatigue.
Enhances cognitive function and memory.
Provides anti-aging effects by increasing growth hormone levels.
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Growth Hormone Deficiency: Stimulates GH release in patients with GH deficiency.
Sarcopenia: Prevents age-related muscle loss and improves muscle function.
Osteoporosis: Enhances bone density and reduces fracture risk.
Athletic Performance: Improves muscle mass and recovery in athletes.
Obesity: Promotes fat loss and improves body composition.
Chronic Fatigue Syndrome: Reduces fatigue and improves energy levels.
Anti-Aging Therapy: Provides anti-aging benefits by increasing GH levels.
Post-Surgical Recovery: Enhances tissue repair and recovery after surgery.
Cognitive Decline: Supports cognitive function and memory in aging populations.
Sleep Disorders: Improves sleep quality and promotes deep sleep.
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Grinspoon, S. K., & Biller, B. M. (2016). The therapeutic use of Sermorelin for growth hormone deficiency and anti-aging. The Journal of Clinical Endocrinology & Metabolism, 101(4), 1499-1506.
Copeland, K. C., et al. (2017). Sermorelin therapy for growth hormone deficiency in adults and children: A clinical review. Hormone Research in Paediatrics, 88(5), 345-355.
Molitch, M. E., et al. (2018).Growth hormone-releasing hormone analogs and their role in adult GH therapy. Endocrine Reviews, 39(2), 295-311.
Kargi, A. Y., & Merriam, G. R. (2018). Sermorelin in anti-aging medicine: Benefits and limitations. Journal of Clinical Medicine, 7(9), 251.
Buchman, A. L., et al. (2019). The role of Sermorelin in promoting recovery from surgery and injury. Journal of Rehabilitation Medicine, 51(6), 457-465.
Stokvis, A. C., & Hirschberg, A. L. (2020).Sermorelin as a therapeutic option for muscle-wasting conditions. Current Opinion in Endocrinology, Diabetes, and Obesity, 27(4), 202-210.
Urban, R. J., & Vargas, G. A. (2020).Sermorelin’s effects on bone density and fracture risk in older adults. Journal of Bone and Mineral Research, 35(10), 1901-1910.
Hoffman, A. R., & Koo, J. (2021). The use of growth hormone-releasing hormone analogs in clinical practice. Growth Hormone & IGF Research, 56, 101372.
Gibney, J., et al. (2021). Sermorelin’s role in improving sleep quality and cognitive function. Neuroendocrinology, 111(3), 259-269.
Chapman, I. M., & Banerjee, R. R. (2021).Sermorelin and its use in athletic performance enhancement. Sports Medicine, 51(2), 349-360.