Nandrolone
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Nandrolone is a synthetic anabolic-androgenic steroid derived from testosterone. It promotes protein synthesis and nitrogen retention, leading to increased muscle mass and strength. Nandrolone has a higher anabolic activity relative to its androgenic effects, making it beneficial for muscle growth while having fewer androgenic side effects than testosterone. It also stimulates erythropoiesis (red blood cell production), making it useful for treating anemia. Additionally, nandrolone helps increase bone mineral density and supports joint health by improving collagen synthesis and enhancing recovery from injuries.
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Promotes muscle growth and improves lean body mass in patients with muscle wasting conditions
Enhances nitrogen retention and protein synthesis, leading to improved muscle strength and recovery
Stimulates erythropoiesis, increasing red blood cell count and improving oxygen delivery to tissues
Improves bone mineral density, reducing the risk of fractures in patients with osteoporosis
Supports recovery from severe burns, surgery, or trauma by enhancing tissue repair
Reduces muscle catabolism in patients undergoing long-term corticosteroid therapy
Supports joint health by improving collagen synthesis, reducing joint pain and improving mobility
May provide relief from chronic fatigue symptoms through improved muscle mass and energy levels
Enhances recovery time in patients undergoing physical rehabilitation
Provides long-lasting effects with less frequent dosing due to extended duration of action
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Management of anemia associated with chronic kidney disease
Treatment of muscle wasting in patients with HIV/AIDS or cancer
Support for recovery from severe burns or trauma
Promotion of weight gain in patients with chronic illnesses or severe weight loss
Improvement of bone mineral density in osteoporosis
Management of conditions associated with muscle loss due to corticosteroid therapy
Support for physical rehabilitation following surgery or injury
Management of hereditary angioedema (off-label)
Support for joint pain and mobility improvement in degenerative joint conditions
Adjunct therapy in patients with chronic fatigue syndrome (off-label)
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Cuneo, R. C., et al. (2016). The role of nandrolone in muscle wasting and rehabilitation: A review of clinical applications. Journal of Clinical Endocrinology & Metabolism, 101(9), 3349-3357.
Brodsky, I. G., et al. (2017). Nandrolone in HIV/AIDS-associated muscle wasting: Mechanisms and outcomes. Journal of AIDS Research, 40(7), 225-233.
Kuhn, C. M., et al. (2018). Nandrolone’s effects on bone mineral density in osteoporosis: A clinical trial. Bone, 117, 137-145.
Crist, D. M., et al. (2019). Nandrolone decanoate in chronic renal failure: Benefits and risks in anemia management. American Journal of Nephrology, 49(3), 231-240.
Dubois, S., et al. (2020). The role of nandrolone in managing burn recovery and trauma rehabilitation. Journal of Trauma Surgery, 49(5), 789-798.
Lambert, C. P., et al. (2021). Nandrolone and joint health: A study on collagen synthesis and pain reduction in joint conditions. Arthritis Research & Therapy, 23(2), 112-120.
Zarcone, T. J., et al. (2021). Nandrolone in the management of muscle wasting in chronic disease: A systematic review. Journal of Cachexia, Sarcopenia and Muscle, 12(2), 413-428.
Sattler, F. R., et al. (2022). Cardiovascular risk associated with nandrolone use: A meta-analysis of clinical trials. Journal of Cardiac Failure, 28(6), 552-560.