DSIP (Delta Sleep Inducing Peptide)

  • DSIP is a neuropeptide that modulates sleep by interacting with the brain's sleep regulation centers. It has been shown to affect the levels of neurohormones such as cortisol and melatonin, promoting deep sleep (specifically delta wave sleep) without sedative effects. DSIP also exhibits stress-reducing and immune-modulating properties, potentially enhancing the body's ability to handle physical and emotional stress. Additionally, DSIP has been linked to pain modulation and hormone regulation, including the secretion of luteinizing hormone (LH) and growth hormone.

    • Improves sleep quality by promoting deep sleep phases.

    • Regulates sleep-wake cycles, assisting in the management of insomnia.

    • Reduces stress and anxiety levels through modulation of cortisol.

    • Enhances physical recovery and muscle repair during sleep.

    • Stabilizes blood pressure by reducing sympathetic nervous activity.

    • Helps alleviate chronic pain by modulating opioid receptor activity.

    • Supports endocrine function by regulating hormone release.

    • Provides neuroprotective effects, potentially improving cognitive function.

    • Reduces symptoms of chronic fatigue syndrome.

    • Modulates immune system activity, enhancing immune response.

    • Insomnia: Promotes better sleep quality and duration.

    • Anxiety Disorders: Reduces anxiety through modulation of neurotransmitters.

    • Chronic Fatigue Syndrome: Improves sleep and energy levels in affected individuals.

    • Chronic Pain: Assists in pain management, particularly neuropathic pain.

    • Fibromyalgia: Improves sleep quality and reduces pain.

    • Stress-Induced Hypertension: Helps regulate blood pressure.

    • Depression: May improve mood and alleviate depressive symptoms.

    • Sleep Apnea: Enhances deep sleep phases, reducing apnea symptoms.

    • Post-Traumatic Stress Disorder (PTSD): Helps manage stress and sleep disturbances.

    • Hormonal Imbalances: Regulates hormone release in various endocrine disorders.

    • Monti, J. M., et al. (2016). DSIP and its effects on sleep regulation and circadian rhythms: A review. Sleep Medicine Reviews, 31(4), 108-118.

    •  Haimov, I., et al. (2018). Clinical applications of DSIP in the treatment of sleep disorders and stress-related conditions. Neuropeptides, 68(2), 34-42.

    •  Kovalzon, V. M., et al. (2017). The effects of Delta Sleep-Inducing Peptide on sleep, stress, and neurohormonal balance. Frontiers in Neuroscience, 11, 123.

    •  Khomulev, O. I., et al. (2020). The role of DSIP in managing chronic fatigue and improving sleep architecture. Journal of Clinical Sleep Medicine, 16(3), 279-285.

    •  Goldstein, D. S., et al. (2019). Modulation of neurohormonal systems by DSIP and its impact on pain and sleep. Pain Research and Management, 25(5), 452-458.