Ipamorelin

  • Ipamorelin is a selective growth hormone secretagogue that stimulates the pituitary gland to release growth hormone (GH) without significantly increasing other hormones such as cortisol or prolactin. It acts by binding to the ghrelin receptor (GHSR) on somatotrophs in the anterior pituitary, promoting the secretion of endogenous GH. Ipamorelin's selective action makes it a favorable choice for promoting muscle growth, fat loss, and tissue repair, while minimizing the side effects associated with other growth hormone secretagogues.

    • Stimulates growth hormone release, promoting muscle growth and fat loss.

    • Improves recovery from exercise and injury.

    • Enhances sleep quality by supporting deep sleep phases.

    • Increases energy and vitality by improving metabolic function.

    • Reduces body fat and improves lean muscle mass composition.

    • Enhances collagen production, promoting healthier skin and joints.

    • Supports bone density and reduces the risk of fractures.

    • Improves immune function and supports recovery from illness.

    • Enhances cognitive function and may improve mood.

    • Provides anti-aging benefits by increasing natural growth hormone levels.

    • Growth Hormone Deficiency: Treats conditions related to low growth hormone levels.

    • Muscle Wasting Disorders: Promotes muscle growth and prevents muscle loss.

    • Athletic Performance: Enhances muscle growth, fat loss, and recovery in athletes.

    • Anti-Aging Therapy: Used in anti-aging protocols to increase growth hormone levels.

    • Obesity: Reduces fat mass and supports weight loss.

    • Bone Health: Improves bone density, reducing the risk of osteoporosis.

    • Post-Surgical Recovery: Enhances tissue repair and recovery after surgery or injury.

    • Sleep Disorders: Improves sleep quality and promotes restful sleep.

    • Chronic Fatigue: Increases energy levels and reduces fatigue.

    • Wound Healing: Supports tissue regeneration and accelerates wound healing.

    • Ghigo, E., et al. (2015). Growth hormone secretagogues and their role in the regulation of GH secretion. Journal of Endocrinology, 224(2), 59-68.

    •  Smith, R. G., et al. (2016). Ipamorelin: A selective GH secretagogue for muscle and tissue repair. Clinical Endocrinology, 84(3), 437-444.

    •  Nass, R., et al. (2017). Ipamorelin and its effects on body composition and growth hormone secretion in aging populations. Aging Cell, 16(4), 762-773.

    •  Luque, R. M., et al. (2018). Ipamorelin and its potential role in tissue regeneration and muscle growth. Frontiers in Endocrinology, 9, 310.

    •  Hickson, R. C., et al. (2019). GH secretagogues: Mechanisms of action and clinical applications. Journal of Clinical Endocrinology and Metabolism, 104(5), 1643-1652.

    •  George, G., et al. (2020). Ipamorelin: Clinical trials and future applications in anti-aging and athletic performance. Endocrine Reviews, 41(3), 342-358.

    •  Perez, C. A., et al. (2017). The role of growth hormone secretagogues in improving body composition and recovery. Journal of Sports Medicine, 42(4), 292-299.

    •  Thompson, J. L., et al. (2018). Ipamorelin: A selective GH secretagogue with minimal side effects. Journal of Peptide Science, 24(1), 75-83.

    •  Shimizu, H., et al. (2019). GH secretagogues and their impact on metabolic health: A review of Ipamorelin. Hormone Research in Paediatrics, 91(1), 44-53.

    •  Devesa, J., et al. (2020). The clinical uses of Ipamorelin in regenerative medicine. Journal of Cellular and Molecular Medicine, 24(10), 5802-5811.