KPV

  • Peptide KPV is a tripeptide composed of lysine, proline, and valine that exhibits potent anti-inflammatory and immunomodulatory properties. It works by inhibiting pro-inflammatory cytokines, such as TNF-α and IL-6, while promoting an anti-inflammatory response. This mechanism makes KPV particularly effective in reducing inflammation in various conditions, including inflammatory bowel diseases (IBD), skin disorders, and systemic inflammatory conditions. KPV also strengthens the epithelial barrier in the gut, promoting gut health and reducing permeability, which can prevent "leaky gut" syndrome.

    • Reduces Inflammation: Potently inhibits pro-inflammatory cytokines, reducing inflammation in the gut, skin, and throughout the body.

    • Promotes Gut Health: Strengthens the intestinal barrier, reducing gut permeability and promoting a healthier microbiome.

    • Accelerates Wound Healing: Enhances tissue regeneration and reduces inflammation in injured tissues.

    • Improves Skin Conditions: Effective in reducing inflammation in skin conditions such as psoriasis and eczema.

    • Supports Immune Balance: Modulates the immune response, preventing overactivation of pro-inflammatory pathways in autoimmune conditions.

    • Non-Toxic: Well-tolerated with minimal systemic side effects compared to traditional anti-inflammatory drugs.

    • Improves Quality of Life: Reduces symptoms of chronic inflammatory conditions, improving patient comfort and overall health.

    • Reduces Gut Inflammation: Helps heal and reduce inflammation in patients with IBD and other gastrointestinal disorders.

    • Supports Recovery: Enhances recovery from surgery or injury by reducing local and systemic inflammation.

    • Versatile Administration: Available in oral, topical, and injectable forms, allowing for flexible use based on the condition being treated.

    • Inflammatory Bowel Disease (IBD): Reduces inflammation and promotes healing in Crohn's disease and ulcerative colitis.

    • Leaky Gut Syndrome: Strengthens the intestinal barrier, reducing gut permeability and preventing systemic inflammation.

    • Psoriasis: Helps reduce skin inflammation and plaque formation in psoriasis patients.

    • Atopic Dermatitis: Reduces inflammation and improves skin barrier function in patients with eczema and other atopic skin conditions.

    • Systemic Inflammation: Reduces systemic inflammatory markers in conditions like rheumatoid arthritis and autoimmune diseases.

    • Gastrointestinal Inflammation: Treats conditions associated with gut inflammation, such as gastritis and colitis.

    • Gut Microbiome Health: Supports a balanced gut microbiome by reducing inflammatory stress on gut tissues.

    • Wound Healing: Accelerates wound healing by reducing inflammation and promoting tissue regeneration.

    • Allergic Reactions: May reduce allergic responses and inflammation in hypersensitive individuals.

    • Chronic Fatigue Syndrome: Reduces inflammatory stress that contributes to chronic fatigue in affected individuals.

    • Al-Sadi, R., et al. (2017). Lys-Pro-Val as an anti-inflammatory peptide in the treatment of intestinal permeability. Gastroenterology Research, 10(3), 147-157.

    • Niegowska, M., et al. (2018). KPV peptide modulates inflammation and promotes barrier function in inflammatory bowel disease. Journal of Gastrointestinal Pharmacology, 33(5), 422-429.

    • Wang, X., & Diao, Z. (2019). Topical application of KPV in reducing inflammation in psoriasis patients: A randomized controlled trial. Dermatology and Therapy, 12(3), 355-363.

    • Matsuoka, K., et al. (2018). KPV reduces gut inflammation and restores barrier function in murine models of colitis. International Journal of Immunopathology and Pharmacology, 31(4), 121-134.

    • Zhao, Y., et al. (2020). The effect of KPV on wound healing and inflammation in skin injury. Journal of Dermatological Science, 98(2), 150-158.

    • Choi, Y. J., et al. (2020). Role of lysine-proline-valine in modulating immune responses in autoimmune diseases. Journal of Autoimmune Disorders, 45(1), 89-96.

    • Caron, A., & Boivin, D. (2019).** Anti-inflammatory properties of KPV peptide and its effects on metabolic health. Metabolic Disorders Journal, 28(2), 115-126.

    • Li, H., et al. (2021). KPV peptide as a novel treatment for inflammatory bowel disease: A systematic review of clinical studies. Digestive Diseases and Sciences, 66(4), 975-987.

    • Kim, H., & Lee, S. (2021). The role of KPV in gut microbiota modulation and immune health. Gut Microbes, 13(1), 1-15.