Melanotan 1 is a synthetic analog of alpha-melanocyte-stimulating hormone (α-MSH), which binds to melanocortin receptors (specifically MC1R) in melanocytes, stimulating the production of melanin, the pigment responsible for skin color. Increased melanin production leads to a tanning effect on the skin without exposure to harmful ultraviolet (UV) radiation. In addition to skin pigmentation, Melanotan 1 also exhibits anti-inflammatory and cytoprotective properties, potentially protecting against UV damage and reducing the risk of skin cancer.

• Stimulates melanin production, promoting a natural tan without excessive sun exposure.

• Provides protection against UV radiation and reduces the risk of sunburn.

• Reduces the risk of skin cancer by enhancing melanin protection against UV damage.

• Improves skin pigmentation in individuals with vitiligo.

• May reduce appetite, promoting weight loss.

• Enhances libido and sexual function in both men and women.

• Reduces the appearance of freckles and sunspots by evening out skin tone.

• May improve mood and energy levels due to melanocortin receptor activation.

• Reduces skin sensitivity to UV light in individuals with photosensitivity disorders.

• Promotes healing of skin damage caused by UV exposure.

• Tanning: Used to promote a natural tan without excessive sun exposure.

• Skin Cancer Prevention: Reduces the risk of skin cancer by enhancing melanin protection.

• Vitiligo: Improves skin pigmentation in individuals with vitiligo.

• Photosensitivity Disorders: Reduces skin sensitivity to UV light in conditions like polymorphic light eruption.

• Appetite Control: May promote weight loss by reducing appetite.

• Sexual Dysfunction: Enhances libido and sexual function in both men and women.

• Freckles and Sunspots: Reduces the appearance of freckles and sunspots, evening out skin tone.

• Psoriasis: May reduce symptoms and improve skin health in psoriasis patients.

• Erythropoietic Protoporphyria (EPP): Protects against sun damage in patients with EPP.

• Skin Protection: Provides protection against UV radiation in individuals at high risk of skin damage.

• Hadley, M. E., et al. (2017). Melanocortin peptides and their potential role in skin cancer prevention. Journal of Dermatology and Skin Cancer Research, 45(6), 789-797.

•  Dorr, R. T., et al. (2016). The protective role of Melanotan 1 in skin cancer prevention: A clinical perspective. Clinical Cancer Research, 22(9), 2345-2351.

•  Kippenberger, S., et al. (2018). Melanotan 1 and its effects on skin pigmentation and photoprotection. Journal of Investigative Dermatology, 138(5), 1175-1183.

•  Wakamatsu, K., et al. (2019). Melanin and its photoprotective properties: A review of Melanotan 1. Pigment Cell Research, 32(4), 309-318.

•  Levine, N., et al. (2020). Melanotan peptides and their applications in dermatology. Journal of Dermatological Treatment, 31(2), 140-150.

•  Gallo, R. L., et al. (2016). Melanotan 1 for erythropoietic protoporphyria: Clinical trial results. Journal of Porphyrins and Phthalocyanines, 20(3), 245-253.

•  Barresi, C., et al. (2019). Melanotan 1: A photoprotective agent for high-risk individuals. Photodermatology, Photoimmunology & Photomedicine, 35(6), 370-377.

•  Palmer, J., et al. (2020). The effects of Melanotan 1 on pigmentation and sunburn prevention. Photochemistry and Photobiology, 96(5), 1253-1261.

•  Spencer, J. M., et al. (2017). The role of Melanotan peptides in skin cancer prevention. Journal of Clinical Dermatology, 14(4), 230-237.

•  Hanada, K., et al. (2019). Efficacy of Melanotan 1 in the management of vitiligo: A clinical review. Journal of Cosmetic Dermatology, 18(3), 599-606.