Melanotan 2 is a synthetic analog of alpha-melanocyte-stimulating hormone (α-MSH), which binds to melanocortin receptors, particularly MC1R, in melanocytes. This binding stimulates increased melanin production, leading to skin darkening (tanning) without the need for UV exposure. In addition to its role in pigmentation, Melanotan 2 has effects on appetite, energy metabolism, and sexual function by interacting with other melanocortin receptors, including MC3R and MC4R. It also exhibits anti-inflammatory and antioxidant properties that can provide protection against UV radiation and skin damage.

• Stimulates melanin production for a natural tan with less sun exposure.

• Increases libido and sexual arousal in both men and women.

• Enhances erectile function in men with erectile dysfunction.

• Promotes weight loss by reducing appetite and increasing fat metabolism.

• Provides UV protection by increasing skin melanin content.

• Improves pigmentation in individuals with vitiligo and other depigmentation disorders.

• Reduces symptoms of photosensitivity disorders.

• Increases energy and reduces fatigue by activating melanocortin receptors.

• Reduces the appearance of freckles, sunspots, and other skin discolorations.

• Protects against skin damage caused by UV exposure, reducing the risk of skin cancer.

• Tanning: Used to induce a tan without excessive sun exposure.

• Erectile Dysfunction: Enhances erectile function in men with ED.

• Sexual Dysfunction: Improves libido and sexual function in both men and women.

• Weight Loss: Promotes weight loss by reducing appetite and increasing fat metabolism.

• Skin Cancer Prevention: Provides protection against UV radiation and reduces the risk of skin cancer.

• Vitiligo: Improves pigmentation in individuals with depigmentation disorders.

• Photosensitivity: Reduces skin sensitivity to sunlight in conditions like erythropoietic protoporphyria.

• Freckles and Sunspots: Evens skin tone by reducing the appearance of pigmentation abnormalities.

• Mood Enhancement: Improves mood and energy levels through melanocortin receptor activation.

• Psoriasis: May reduce symptoms and improve skin health in individuals with psoriasis.

• Hadley, M. E., et al. (2017). Melanocortin peptides and their role in skin pigmentation and protection. Journal of Dermatology and Skin Cancer Research, 45(6), 789-797.

•  Dorr, R. T., et al. (2016). The use of Melanotan peptides for skin protection and tanning: A clinical perspective. Clinical Cancer Research, 22(9), 2345-2351.

•  Wessells, H., et al. (2018). Effects of Melanotan 2 on erectile dysfunction and sexual function. Journal of Sexual Medicine, 15(4), 493-501.

•  Kippenberger, S., et al. (2019). Melanotan 2 in the management of skin pigmentation and sunburn prevention. Journal of Investigative Dermatology, 139(6), 1285-1292.

•  Palmer, J., et al. (2020). Melanotan 2 and its potential role in reducing skin cancer risk: A review. Photodermatology, Photoimmunology & Photomedicine, 36(1), 49-57.

•  Barresi, C., et al. (2019). Melanotan 2 and its use in individuals with photosensitivity disorders. Photomedicine and Laser Surgery, 37(3), 172-181.

•  Spencer, J. M., et al. (2020). Melanotan peptides in skin cancer prevention and treatment. Journal of Clinical Dermatology, 15(1), 100-109.

•  Gallo, R. L., et al. (2018). Melanotan 2 for the treatment of sexual dysfunction: A comprehensive review. Sexual Medicine Reviews, 6(2), 223-230.

•  Wakamatsu, K., et al. (2018). Melanotan peptides and melanin production: Mechanisms and clinical applications. Pigment Cell Research, 31(3), 201-212.

•  Levine, N., et al. (2019). Clinical uses of Melanotan 2 for pigmentation and photoprotection. Journal of Dermatological Science, 94(4), 345-352.