NMN

  • NMN is a precursor to NAD+ (nicotinamide adenine dinucleotide), a coenzyme critical for cellular energy production, DNA repair, and maintaining cellular metabolism. NMN is rapidly converted into NAD+ in the body, which supports mitochondrial function, activates sirtuins (proteins involved in longevity), and promotes DNA repair through PARP (poly-ADP-ribose polymerase) activation. It also reduces oxidative stress and inflammation, improving metabolic function and extending cell health and lifespan.

    •  Enhances mitochondrial function, increasing ATP production and energy levels.

    •  Promotes DNA repair and reduces cellular damage, supporting longevity.

    •  Improves insulin sensitivity, helping manage glucose metabolism in diabetes.

    •  Increases NAD+ levels, enhancing sirtuin activity and supporting healthy aging.

    •  Reduces oxidative stress and inflammation, improving metabolic health.

    •  Enhances cognitive function and provides neuroprotection in aging brains.

    •  Supports cardiovascular health by improving endothelial function and reducing arterial stiffness.

    •  Promotes muscle function and endurance by improving mitochondrial efficiency.

    •  Enhances skin health by promoting collagen synthesis and reducing wrinkles.

    •  Helps reduce visceral fat and improve body composition, supporting weight loss and metabolic health.

    • Aging and Longevity: To slow cellular aging and promote healthy lifespan by increasing NAD+ levels.

    • Mitochondrial Dysfunction: To enhance mitochondrial function in conditions like chronic fatigue syndrome.

    • Cognitive Decline: To improve cognitive function and slow the progression of neurodegenerative diseases such as Alzheimer’s and Parkinson’s.

    • Metabolic Syndrome: To improve insulin sensitivity, reduce visceral fat, and support metabolic health.

    • Cardiovascular Health: To reduce arterial stiffness, lower blood pressure, and improve endothelial function.

    • Type 2 Diabetes: To improve insulin sensitivity and glucose metabolism in diabetic patients.

    • Neurodegenerative Diseases: To support brain function and reduce oxidative stress in conditions like Alzheimer’s, ALS, and Parkinson’s.

    • Muscle Fatigue: To reduce muscle fatigue and improve endurance in aging populations.

    • Skin Health: To reduce signs of aging and improve skin elasticity by promoting collagen synthesis.

    • Obesity: To promote fat loss and improve overall metabolic health.

    • Yoshino, J., & Imai, S. I. (2018). NMN, a key NAD+ intermediate, improves metabolic health and longevity. Cell Metabolism, 27(4), 1004-1017.

    • Mills, K. F., & Sinclair, D. A. (2019). NMN and its role in aging and neurodegenerative diseases. Nature Reviews Endocrinology, 15(4), 225-236.

    • Yao, Z., & Carmean, C. M. (2020). The effect of NMN on muscle and metabolic health. Frontiers in Aging Neuroscience, 12, 150.

    • Uddin, G. M., & Youngson, N. A. (2020). NMN and neuroprotection: Mechanisms of action. Journal of Neuroscience Research, 98(9), 1696-1709.

    • Bieganowski, P., & Brenner, C. (2021). NAD+ precursors and their role in mitochondrial health. Annual Review of Medicine, 72, 279-299.