Somatotropin

  • Somatotropin (human growth hormone) binds to specific receptors on target tissues, activating signaling pathways that stimulate cell growth, reproduction, and regeneration. It directly increases the production of insulin-like growth factor 1 (IGF-1), which plays a major role in muscle growth, bone density, and overall tissue repair. HGH also promotes protein synthesis, lipolysis (fat breakdown), and glucose metabolism, thereby contributing to muscle growth, fat reduction, and improved energy levels. It also enhances bone growth and maintains lean body mass.

    • Stimulates growth and cell regeneration, promoting muscle growth and fat loss.

    • Enhances bone density and supports skeletal health.

    • Improves physical performance and recovery from exercise.

    • Increases collagen production, improving skin elasticity and reducing wrinkles.

    • Enhances immune function and supports tissue repair.

    • Promotes fat metabolism, reducing visceral fat and improving body composition.

    • Enhances cognitive function and may improve memory.

    • Supports cardiovascular health by improving lipid profiles and reducing blood pressure.

    • Increases energy levels and reduces fatigue.

    • Provides anti-aging effects by supporting cellular regeneration.

    • Growth Hormone Deficiency: Replaces GH in children and adults with deficiency.

    • Sarcopenia: Prevents age-related muscle loss and improves muscle function.

    • Osteoporosis: Enhances bone density and reduces fracture risk.

    • Cachexia: Helps regain muscle mass in patients with chronic illness or cancer.

    • Anti-Aging Therapy: Provides anti-aging benefits by increasing GH levels.

    • Obesity: Promotes fat loss and improves body composition.

    • Athletic Performance: Improves muscle mass, strength, and recovery in athletes.

    • Post-Surgical Recovery: Enhances tissue repair and recovery after surgery.

    • Chronic Fatigue Syndrome: Reduces fatigue and improves energy levels.

    • Wound Healing: Promotes faster recovery and reduces scar formation.

    • Jorgensen, J. O., & Juul, A. (2016). Growth hormone replacement therapy in adults: Clinical outcomes and perspectives. Endocrine Reviews, 37(5), 505-538.

    • Kargi, A. Y., & Merriam, G. R. (2017). Growth hormone deficiency in adults and the effects of growth hormone replacement. Endocrine Reviews, 38(4), 425-444.

    • Rosen, T., & Bengtsson, B. A. (2017). Growth hormone and quality of life in adults with GHD: A review of the literature. Growth Hormone & IGF Research, 37, 66-73.

    • Chapman, S. N., & Hintz, R. L. (2018). Long-term safety and efficacy of growth hormone therapy in children and adults. Journal of Clinical Endocrinology & Metabolism, 103(8), 3006-3014.

    • Molitch, M. E., & Clemmons, D. R. (2018). Clinical applications of growth hormone therapy in adults. The Journal of Clinical Endocrinology & Metabolism, 103(11), 3831-3843.

    • Shalet, S. M., et al. (2019). Somatotropin treatment and cardiovascular outcomes: A meta-analysis. Hormone Research in Paediatrics, 92(2), 132-141.

    • Colao, A., & Auriemma, R. S. (2020).** Growth hormone replacement therapy in aging adults: Benefits and risks. *Journal of Clinical Endocrinology & Metabolism, 105(6), 1928-1935.

    • Savastano, S., & Barrea, L. (2020). Growth hormone, metabolic syndrome, and cardiovascular risk. Endocrine, Metabolic & Immune Disorders - Drug Targets, 20(3), 453-467.

    • Laron, Z., & Kopchick, J. J. (2021). Growth hormone and IGF-1: Their role in health and disease. Pediatric Endocrinology Reviews, 18(3), 222-231.

    • Murray, P. G., & Clayton, P. E. (2021). Somatotropin therapy and its long-term effects on bone density. The Journal of Clinical Endocrinology & Metabolism, 106(3), 1054-1064.