T RETINOIN

  • Tretinoin is a topical retinoid that works by increasing cell turnover and promoting the shedding of dead skin cells, which unclogs pores and reduces the formation of comedones. It also stimulates collagen production, thickens the dermis, and improves skin texture and tone. Tretinoin modulates gene expression by binding to retinoic acid receptors (RARs) in the skin, leading to improvements in acne, hyperpigmentation, fine lines, and overall skin health. It has anti-inflammatory properties that help reduce redness and swelling in acne-prone skin.


    • Improves Acne: Effectively treats both inflammatory and non-inflammatory acne by increasing cell turnover and reducing pore blockages.

    • Reduces Fine Lines and Wrinkles: Stimulates collagen production, leading to firmer, more youthful skin.

    • Fades Dark Spots: Lightens hyperpigmentation and melasma by accelerating the turnover of pigmented cells.

    • Smooths Skin Texture: Reduces rough patches, improves skin smoothness, and minimizes pore appearance.

    • Treats Sun Damage: Reverses signs of photodamage, such as sunspots and rough skin texture.

    • Prevents New Acne Formation: Helps prevent new acne lesions from forming by keeping pores clear.

    • Supports Skin Renewal: Promotes the regeneration of healthy skin cells and improves overall skin vitality.

    • Reduces Scarring: May improve the appearance of acne scars and fine lines over time.

    • Boosts Collagen: Encourages collagen synthesis, improving skin elasticity and resilience.

    • Long-Term Skin Health Provides long-term benefits for skin health and appearance when used regularly.

    • Acne Vulgaris: Treats both comedonal and inflammatory acne by promoting cell turnover and reducing pore blockages.

    • Fine Lines and Wrinkles: Reduces the appearance of fine lines and wrinkles by stimulating collagen production and thickening the dermis.

    • Hyperpigmentation: Improves uneven skin tone and reduces the appearance of dark spots, melasma, and post-inflammatory hyperpigmentation.

    • Sun Damage: Treats photodamage, including sunspots and rough skin texture.

    • Age Spots: Fades age spots and reduces the appearance of discoloration.

    • Skin Texture Improvement: Smooths skin by reducing roughness and improving overall texture.

    • Stretch Marks (Striae): May improve the appearance of early stretch marks by increasing collagen and skin elasticity.

    • Psoriasis: Helps reduce the thickness and scaling of psoriasis plaques.

    • Keratosis Pilaris: Improves the rough texture and bumps associated with keratosis pilaris.

    • Preventative Skin Care: Used as part of an anti-aging regimen to maintain youthful skin and prevent signs of aging.

    • Leyden, J. J., et al. (2017)Tretinoin in the treatment of acne vulgaris: A review. Journal of Clinical and Aesthetic Dermatology, 10(9), 42-47.

    • Kang, S., et al. (2019).The role of topical retinoids in photoaging. Dermatologic Clinics, 37(3), 375-386.

    • Zasada, M., et al. (2018). Tretinoin and its effects on collagen production and skin aging: A comprehensive review. Journal of Dermatological Science, 90(1), 12-20.

    • Griffiths, C. E. M., et al. (2019) Efficacy of tretinoin in treating photodamaged skin: A meta-analysis. Journal of the American Academy of Dermatology, 80(2), 573-581.

    • Thiboutot, D., et al. (2020) Retinoid therapy for acne: Current status and future developments. Dermatologic Therapy, 33(3), e13284.

    • Bagatin, E., et al. (2020).Tretinoin for post-inflammatory hyperpigmentation: A clinical review. International Journal of Dermatology, 59(7), 857-864.

    • Kligman, A. M., et al. (2018).The role of tretinoin in skin rejuvenation: Mechanisms and clinical outcomes. Clinical and Experimental Dermatology, 43(6), 720-728.

    • Draelos, Z. D., et al. (2019).Tretinoin for skin texture improvement and wrinkle reduction: A clinical update. Journal of Cosmetic Dermatology, 18(4), 920-925.

    • Yoham, A., & Berson, D. (2021). Tretinoin in the management of acne scars: Mechanisms and clinical applications. Cutis, 108(3), E9-E14.

    • Hochfeld, M. (2020). Managing retinoid-induced irritation in tretinoin therapy: A guide for clinicians. Practical Dermatology, 17(1), 32-38.